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Rubella IgM

Product Description

The Rubella IgM test is a two-step capture chemiluminescent immunoassay (CLIA), for use on IDS automated analyzers, for quantitative determination of specific IgM class antibodies directed against the Rubella virus in samples of human serum or plasma (K3-EDTA, Sodium Citrate).

This assay is used as a diagnostic aid when assessing immunity status of patients related to Rubella virus infection.

  • Complete panel for the diagnosis of Rubella with IgG, IgM and IgG Avidity testing
  • Significant sensitivity in the primary infection for both IgG and IgM tests
  • The high specificity of the IgM test allows the observation of decreasing IgM concentration three months after the onset of the infection
  • The capture method of Rubella IgM does not require the confirmatory test
    1. DM Horstmann. Rubella in : Evans A.S., ed. Viral infections of humans : epidemiology and control. New York: Plenum Press,1976; 409-427.
    2. Askin DF. Intrauterine infections. Neonatal.Netw. 2004; 23(5):23-30.
    3. Cooper LZ,Alford Jr.CA. Rubella. In : Remington JS, Klein JO, editors. Infectious Diseases of the Fetus and Newborn infant. Philadelphia,PA : Elsevier Saunders ; 2006 : 893-926.
    4. Atreya CD, Mohan KV, Kulkami S. Rubella virus and birth defects : molecular insights into the viral teratogenesis at the cellular level. A. Clin. Mol. Terato. 2004; 70 (7): 431-7.
    5. Department of Vaccines and Biologicals, WHO. Report of a meeting on preventing congenital Rubella syndrome : immunization strategies, surveillance needs. Geneva : World Health Organization,2000.
    6. Best JM, Banatvala JE. Rubella. In . AJ Zuckerman, JE Banatvala, JR Pattison,eds. Principles and practice of clinical virology. 4th Chichester : John Wiley,2000: 387-418.
    7. Best JM, O’Shea S, Tipples G,Davies N, Al-Khusaiby SM, Krause A, Hesketh LM, Jin L, Enders G. Interpretation of Rubella serology in pregnancy-pitfalls and problems. BMJ. 2002;325 (7356): 147-148
    8. Banatvala JE and Brown DWG. 2004. Rubella. Lancet 363 : 1127-1139
    9. Banatvala JE,Best JM, O’Shea S,Dudgeon JA. Persistence of Rubella antibodies following vaccination : detection of viremia following experimental challenge. Rev. Infect. Dis 1985; 7(suppl 1): S86-90

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Rubella IgM

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