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Liver Disease

A fully automated assay panel for aiding the diagnosis of autoimmune liver diseases through quality and efficiency immunoassays

Although autoimmune liver diseases are rare, their differential diagnosis from non-autoimmune liver diseases is important in the treatment decision. Among autoimmune liver diseases are:

Autoimmune Hepatitis is a chronic, inflammatory disease starting as acute hepatitis and progressing to chronic liver disease and cirrhosis or liver failure1.

Primary biliary cirrhosis (PBC) is an autoimmune disease causing a chronic inflammation of the intrahepatic bile ducts, leading to hepatic fibrosis and cirrhosis and ultimately may lead to the need for a liver transplant2,3.

Our Autoimmune Liver Disease panel aids laboratories in the diagnosis and monitoring of these conditions’ through enhanced quality and workflow efficacy immunoassays:

  • Anti-AMA (M2) IgG for aiding the diagnosis of PBC 4.
  • Anti-LKM-1 IgG for aiding the diagnosis of Autoimmune Hepatitis5.
  1. J Hepatol. 2015 Oct;63(4):971-1004.
  2. Lindor KD et al. Hepatology 2009 ; 50 : 291-308.
  3. Crosignani A et al. World J Gastroenterol. 2008 Jun 7 ; 14(21) : 3313-27.
  4. Hirschfield GM et al. Gut. 2018 Sep;67(9):1568-1594.
  5. Tanaka A. Gut Liver. 2020 Jul 15;14(4):430-438.

Liver Disease Products

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Assays Certification Platform Clinical Area Portfolio RUO/IVD
AMA (M2) CE Marked i10iSYS Liver Disease Autoimmunity IVD
LKM-1 CE Marked i10iSYS Liver Disease Autoimmunity IVD

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Ruo/IVD

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