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N-MID® Osteocalcin ELISA

Product Description

For determination of osteocalcin, an indicator of osteoblastic activity, in human serum and plasma. Results are to be used in conjunction with other clinical and laboratory data to aid the clinician in the monitoring of postmenopausal osteoporosis and assessment of changes in bone metabolism in response to therapy.

  • Easy to perform
  • The N-MID® Osteocalcin ELISA recognises both intact and large N-MID® osteocalcin fragments with equal affinity
  • N-MID® Osteocalcin ELISA measuring total osteocalcin, providing a more stable and reproducible result than assays measuring intact osteocalcin only
  • Robust assay format
  • Excellent correlation with automated methods
  • Part of a complete clinical assay panel supporting bone disease management
    1. Bjarnason NH. et al., Tibolone: prevention of bone loss in late postmenopausal women.J Clin Endocrinol Metab (1996) 81: 2419-2422.
    2. Christiansen C. et al., Dose dependent effects on bone resorption and formation of intermittently administered intravenous ibandronate. Osteoporos Int (2003) 14: 609-613.
    3. Junqueira PA. et al., Comparison of bone remodeling indicators in climacteric women.Int J Fertil Womens Med (2002) 47: 174-181.
    4. Marcus R. et al., The relationship of biochemical markers of bone turnover to bone density changes in postmenopausal women: results from the Postmenopausal Estrogen/Progestin Interventions (PEPI) Trial.J Bone Mineral Res (1999) 14: 1583-1595.
    5. Rosenquist C. et al., Measurement of a more stable region of osteocalcin in serum by ELISA with two monoclonal antibodies. Clin Chem (1995) 41:1439-1445.

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N-MID® Osteocalcin ELISA

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