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LISA-TRACKER anti-Adalimumab

Product Description

LISA-TRACKER anti-Adalimumab is an enzyme linked immunoassay (ELISA) for the quantitative determination of human anti-Adalimumab antibodies in human serum samples.

  • Comprehensive menu in inflammatory diseases and oncology
  • Validated on principle drug and biosimilars
  • Ready to use reagents
  • Standardised protocols from sample collection to result interpretation
  • Automation ready – protocols available on several open platform ELISA systems
    1. Assa A & al. Proactive Monitoring of Adalimumab Trough Concentration Associated With Increased Clinical Remission in Children With Crohn’s Disease Compared With Reactive Monitoring Gastroenterology . 2019 Oct;157(4):985-996.e2.
    2. Bartelds GM & al. Development of antidrug antibodies against adalimumab and association with disease activity and treatment failure during long-term follow-up. JAMA. 2011 Apr 13;305(14):1460-8.
    3. Gibson DJ & al. Review article: determination of the therapeutic range for therapeutic drug monitoring of adalimumab and infliximab in patients with inflammatory bowel disease.Aliment Pharmacol Ther. 2020 Mar;51(6):612-628.
    4. Labetoulle R & al. Prolonged Persistence of Adalimumab Transferred From Mother to Infant During Pregnancy. Ann Intern Med. 2018 Mar 6.
    5. Quistrebert J & al. Incidence and risk factors for adalimumab and infliximab anti-drug antibodies in rheumatoid arthritis: A European retrospective multicohort analysis. Semin Arthritis Rheum. 2018 Oct 12. pii: S0049-0172(18)30176-8.
    6. Radstake TRDJ & al. Formation of antibodies against infliximab and adalimumab strongly correlates with functional drug levels and clinical responses in rheumatoid arthritis. Ann Rheum Dis 2009;68:1739–1745.

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