- Comprehensive menu in inflammatory diseases and oncology
- Validated on principle drug and biosimilars
- Ready to use reagents
- Standardised protocols from sample collection to result interpretation
- Automation ready – validated on several open platform ELISA systems
LISA-TRACKER anti-Adalimumab is an enzyme linked immunoassay (ELISA) for the quantitative determination of human anti-Adalimumab antibodies in human serum samples.
Anti-TNFα are therapeutic agents widely used to treat patients with various inflammatory diseases. Adalimumab is one of the anti-TNFα recommended for the treatment of the rheumatoid arthritis, Crohn’s disease, ankylosing spondylitis, etc. This fully humanised monoclonal antibody is able to bind TNFα. It blocks the action of TNFα responsible for the inflammatory state. However, during the treatment, some patients can develop antibodies against Adalimumab. Consequently, the plasma level of anti-TNFα decreases and simultaneous the disease symptoms reappear or increase.
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- Van den Bemt BJF et al. Anti-infliximab antibodies are already detectable in most patients with rheumatoid arthritis halfway through an infusion cycle: an open-label pharmacokinetic cohort study. BMC Musculoskeletal Disorders 2011.
- Metcalfe C et al. World Health Organization, WHO Expert Committee on Biological Standardization. (2017). Report on a collaborative study for proposed 1st international standard for Infliximab. WHO/BS/2017.2323.
LISA-TRACKER Duo Adalimumab
ImmunoTROL LISA-TRACKER Adalimumab
ImmunoTROL LISA-TRACKER anti-Adalimumab