LISA-TRACKER Duo Ustekinumab
Product Description
LISA-TRACKER Duo Ustekinumab is an enzyme linked immunoassay (ELISA) for the quantitative determination of Ustekinumab (antibody anti-Interleukin 12 and 23) and anti-Ustekinumab antibodies in human serum samples.
- Comprehensive menu in inflammatory diseases and oncology
- Validated on principle drug and biosimilars
- Ready to use reagents
- Standardised protocols from sample collection to result interpretation
- Automation ready – protocols available on several open platform ELISA systems
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- Adedokun O.J. et al. Pharmacokinetics and Exposure Response Relationships of Ustekinumab in Patients With Crohn’s Disease, 2018, 154(6), 1660–1671.
- Benson JM et al. Discovery and mechanism of Ustekinumab a human monoclonal antibody targeting interleukin-12 and interleukin-23 for treatment of immune-mediated disorders, mAbs, 2011, 3:6, 535-545.
- Feagan B.G. et al. Ustekinumab as Induction and Maintenance Therapy for Crohn’s Disease, N Engl J Med 2016;375:1946-60.
- Lebwohl M and al. Review of ustekinumab, an interleukin-12 and interleukin-23 inhibitor used for the treatment of plaque psoriasis, Therapeutics and Clinical Risk Management, 2010:6, 123-141.
- Papp KA et al. Long-term safety of Ustekinumab in patients with moderate-to-severe psoriasis: final results from 5 years of follow-up, Br. J. Dermatol, 2013, 168(4):844-54.
- Rutgeerts P et al. Efficacy of Ustekinumab for Inducing Endoscopic Healing in Patients With Crohn’s Disease, Gastroenterology, 2018, 155(4), 1045–1058.
- Product Code: LTU-005
- Number of Tests: 2 x 48
- Sample Type: Serum or plasma
- Sample Volume: 100 μL (following predilution)
- Assay Range: Ustekinumab: 0.04 – 1 μg/mL and 0.4 – 10 μg/mL / Anti-Ustekinumab: 3 – 100 AU/mL
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