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LISA-TRACKER anti-Ustekinumab

Product Description

LISA-TRACKER anti-Ustekinumab is an enzyme linked immunoassay (ELISA) for the quantitative determination of anti-Ustekinumab antibodies in human serum samples.

  • Comprehensive menu in inflammatory diseases and oncology
  • Validated on principle drug and biosimilars
  • Ready to use reagents
  • Standardised protocols from sample collection to result interpretation
  • Automation ready – protocols available on several open platform ELISA systems
    1. Adedokun O.J. et al. Pharmacokinetics and Exposure Response Relationships of Ustekinumab in Patients With Crohn’s Disease, 2018, 154(6), 1660–1671.
    2. Benson JM et al. Discovery and mechanism of Ustekinumab a human monoclonal antibody targeting interleukin-12 and interleukin-23 for treatment of immune-mediated disorders, mAbs, 2011, 3:6, 535-545.
    3. Feagan B.G. et al. Ustekinumab as Induction and Maintenance Therapy for Crohn’s Disease, N Engl J Med 2016;375:1946-60.
    4. Lebwohl M and al. Review of ustekinumab, an interleukin-12 and interleukin-23 inhibitor used for the treatment of plaque psoriasis, Therapeutics and Clinical Risk Management, 2010:6, 123-141.
    5. Papp KA et al. Long-term safety of Ustekinumab in patients with moderate-to-severe psoriasis: final results from 5 years of follow-up, Br. J. Dermatol, 2013, 168(4):844-54.
    6. Rutgeerts P et al. Efficacy of Ustekinumab for Inducing Endoscopic Healing in Patients With Crohn’s Disease, Gastroenterology, 2018, 155(4), 1045–1058.

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