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Ostase® BAP EIA

Product Description

For the determination of bone-specific alkaline phosphatase (BAP), an indicator of osteoblastic activity in human serum. Results can be used as an aid in the management of post-menopausal osteoporosis and Paget’s disease.

  • Fast turnaround time
  • Measures bone specific alkaline phosphatase (BAP) with low interference from other alkaline phosphatase isoforms
  • Excellent limit of detection (<1.0 μg/L)
  • Clinically relevant assay range – accommodates samples in a wide dynamic range
  • Excellent correlation with automated methods
  • Part of a complete assay panel supporting bone disease management
    1. Epstein S. Serum and urinary markers of bone remodeling: assessment of bone turnover. Endocrine Reviews 9:437-448, 1988.
    2. Whyte MP. Alkaline phosphatase and the measurement of bone formation, Clinical Disorders of Bone and Mineral Metabolism. Potts JT and Frame B, eds., pp. 120-125, 1983.
    3. Garnero P and Delmas P. Assessment of the serum levels of bone alkaline phosphatase with a new immunoradiometric assay in patients with metabolic bone disease. J Clin Endocrin Metab 77:1046-1053, 1993.
    4. Cooper EH, Whelan P, and Purves D. Bone alkaline phosphatase and prostate-specific antigen in the monitoring of prostate cancer. The Prostate 25:236-242, 1994.
    5. Van Straalen JP, Sanders E, Prummel MF, et al. Bone alkaline phosphatase as indicator of bone formation. Clin Chim Acta 201:27-33, 1991.
    6. Merkow RL and Lane JM. Metabolic bone disease and Paget’s disease in the elderly: II. Paget’s Disease. Clin Rheum Dis 12:70, 1986.

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