Throughout life, old bone is constantly removed (resorption) and replaced by new bone (formation). This continual process is essential for the maintenance of healthy bone mass and micro-architecture. Accelerated bone mass resorption can occur to women in postmenopausal years. Osteoporosis is a disease characterised by low bone density and reduced structural strength of the bone, leading to increased risk of bone fracture. Osteoporosis affects approximately 30% of postmenopausal women in the US and Europe.1 Around the world 1 in 3 women and 1 in 5 men are at risk of osteoporotic fracture.1

Changes in bone turnover can be assessed by using the comprehensive IDS bone turnover test panel, which offers laboratories an in-vitro alternative to ex-vivo and in-vivo methods. Use of IDS bone turnover assays, enables clinicians to quantify bone formation and resorption levels in order to assist with monitoring.

1. www.iofbonehealth.org

Related disease area: Growth, Calcium Metabolism

Bone Metabolism

Portfolio Area Certification Clinical Area Product Type RUO/IVD
IDS-iSYS TRAcP 5b (BoneTRAP®)

CE Marked

Automated IVD
Serum Crosslaps® (CTX-I) ELISA

CE Marked
FDA Cleared

Manual IVD
Urine BETA CrossLaps® (CTX-I) ELISA

FDA Cleared

Manual IVD
Urine CrossLaps® (CTX-I) EIA

CE Marked

Manual IVD
IDS-iSYS CTX-I (CrossLaps®)

CE Marked
FDA Cleared

Automated IVD
BoneTRAP® (TRAcP 5b) ELISA

CE Marked

Manual IVD
Alpha CrossLaps® (CTX-I) ELISA

CE Marked
FDA Cleared

Manual IVD
Ostase® BAP EIA

FDA 510(k) Cleared
CE Marked

Manual IVD
N-MID® Osteocalcin ELISA

FDA 510(k) Cleared
CE Marked

Manual IVD
IDS-iSYS Ostase® BAP

CE Marked

Automated IVD
IDS-iSYS N-MID® Osteocalcin

CE Marked

Automated IVD
IDS-iSYS Intact PINP

CE Marked

Automated IVD

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