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Sm

Product Description

The Sm test is a chemiluminescent immunoassay (CLIA), for use on IDS automated analyzers. It is used for the quantitative determination of the specific IgG antibodies directed against the Sm antigens in human samples of serum or plasma (EDTA).

    1. CA von Mühlen, EM Tan. Autoantibodies in the diagnosis of systemic rheumatic diseases. Sem Arthr Rheum 1995; 24: 323-58.
    2. RL Humbel. Auto-immunité, auto-anticorps et maladie. In : Humbel RL, ed. Autoanticorps et maladies autoimmunes, Paris, France : Edition Scientifiques Elsevier; 1997: 17-20.
    3. PN Hollingsworth, SC Pummer, RL Dawkins. Antinuclear antibodies. In : Peter JB, Shoenfeld Y, eds. Autoantibodies. Amsterdam, The Netherlands : Elsevier Science BV; 1996: 74-90.
    4. CA Slater, RB Davis, RH Shmerling. Antinuclear antibodies testing. A study of clinical utility. Arch Int Med 1996; 156: 1421-5.
    5. RL Humbel. Detection of antinuclear antibodies by immunofluorescence. In : van Venrooij, Maini RN eds. Manual of Biological Markers of Disease. Dordrecht, The Netherlands : Kluwer; 1993: A2:1-16.
    6. National Committee for Clinical Laboratory Standardization. Quality assurance for the indirect immunofluorescence test for autoantibodies to nuclear antigen ( IF-ANA ). Approved Guideline. Wayne, PA: NCCLS I/LA2-A, vol. 16 ( 11 ); 1996.
    7. CL Will, R Luhrmann. Spliceosomal UsnRNP biogenesis, structure and function. Curr Opin Cell Biol 2001; 13:290-301.
    8. GW Zieve, PR Khusial. The anti-Sm immune response in autoimmunity and cell biology. Autoimmun Rev 2003; 2: 235-40.
    9. MT McClain, PA Ramsland, KM Kaufman, JA James. Anti-Sm autoantibodies in systemic lupus erythematosus target highly basic surface structures of complexed spliceosomal autoantigens. J Immunol 2002; 168: 2054-62.
    10. SL Peng, JE Craft. Spliceosomal snRNPs autoantibodies. In : Peter JB, Shoenfeld Y, eds. Autoantibodies. Amsterdam : Elsevier Science BV, 1996, pages 774-82.
    11. Y Sherer, A Gorstein, MJ Fritzler, Y Shoenfeld. Autoantibody explosion in systemic lupus erythematosus. Semin Arthritis Rheum 2004; 34: 501-37.
  • Product Code: IS-AI1106
  • Number of Tests: 50
  • Sample Type: Human Serum or Plasma (EDTA)
  • Sample Volume: 4 µL
  • Assay Range: 0-320 AU/mL
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