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Product Description

Double antibody separation has been commonly used since the earliest days of radioimmunoassay (RIA)1,2 and is very reliable. Less demanding procedures have been sought, in particular solid phase antibody techniques3,4.

  • The use with CrossLaps® for Culture (CTX-I) ELISA does not require termination of the osteoclast culture (In contrast to pit staining and scoring)
  • Several samplings can be obtained from the same dentine disc, allowing for example, reversibility measurement of osteoclast activity in response to given compounds
    1. Hales, C.N. and Randle, P.J. (1963). Biochem. J., 88, 137.
    2. Koninckx, Ph., Bouillon, R. and De Moor, P. (1976). Acta Endocr. (Kbh)., 81, 45-53.
    3. Morgan, C.R. and Lazarow, A. (1963). Diabetes, 12, 115.
    4. Sluiter, W.J. et al. (1972). Clin. Chim. Acta., 42, 255.

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