CrossLaps® for Culture (CTX-I) ELISA
Product Description
For determination of bone related degradation products from C-terminal telopeptides of type I collagen in bone cell culture supernatant.
- Supports the screening of early phase anti-resorptive drug development1-3
- Allows high throughput screening of osteoclastic resorptive activity
- Enables multiple testing of single osteoclast cultures over time
- Objective assessment of in vitro bone resorption
- High correlation to resorption pit area
- Allows dynamic monitoring of bone cultures
- Easy to perform – one step incubation
- Part of a complete assay panel supporting bone research
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- Burgeson RE. New collagens, new concepts. Annu Rev Cell Biol (1988);4:551-77.
- Stroup et al. Potent and selective inhibition of human cathepsin K leads to inhibition of bone resorption in vivo in a nonhuman primate. J Bone Miner Res (2001);16:1739-1746
- Breuil et al. Human osteoclast formation and activity in vitro: effects of alendronate. J Bone Miner Res (1998);13:1721-1729
- Product Code: AC-07F1
- RUO/IVD: RUO
- Number of Tests: 96 wells
- Sample Type: Cell Culture Supernatant
- Sample Volume: 30 µL
- Assay Range: 0.75 – 112.7 nM
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