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Product Description

For the determination of rat tartrate-resistant acid phosphatase 5b (TRAcP 5b) in rat serum.

  • Derived exclusively from bone-resorbing osteoclasts
  • Low diurnal variation
  • No dietary influences
  • No accumulation into the circulation due to renal or hepatic impairment
  • Only bone resorption marker useful in renal research and for non-fasting samples
  • Part of a complete assay panel supporting bone research
    1. Lam KW, Li CY, Yam LT, et al. 1981 Comparison of the tartrate-resistant acid phosphatase in Gaucher’s disease and leukemic reticuloendotheliosis. Clin Biochem 14:177-181.
    2. Alatalo SL, Penq Z, Janckila AJ, et al. 2003 A novel immunoassay for the determination of tartrate-resistant acid phosphatase 5b from rat serum. J Bone Miner Res 18:134-139.
    3. Alatalo SL, Ivaska KK, Waguespack SG, et al. 2004 Osteoclast-derived serum tartrate-resistant acid phosphatase 5b in Albers-Schonberg disease (type II autosomal dominant osteopetrosis). Clin Chem 50:883-890.
    4. Rissanen JP, Suominen MI, Oksala R, et al. 2006 The ratio of osteoclast activity/osteoclast number (CTX/TRACP 5b) is a useful parameter in experimental rat models of osteoporosis. J Bone Miner Res 21 (Suppl 1): Abstract SU105.

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