Rat/Mouse PINP EIA
Product Description
For determination of N-terminal propeptide of type I procollagen (PINP) in rat or mouse serum or plasma samples.
- Unique – the first commercially available EIA to quantify type I collagen formation in rat or mouse specimens:
- Ideal for rodents – only 5μL per well
- Flexible – serum or plasma samples can be used
- Complementary – use in conjunction with IDS RatTRAP™ (TRAcP 5b) ELISA or RatLaps® (CTX-I) EIA
- Part of a complete assay panel supporting bone research
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- Risteli J, Risteli L 2006 Products of bone collagen metabolism. In: Seibel MJ, Robins SP, BilezikianJP, editors. Dynamics of bone and cartilage metabolism. Principles and clinical applications, second edition. London: Academic Press. p. 391-405.
- Melkko J, Kauppila S, Niemi S, et al. 1996 Immunoassay for intact amino-terminal propeptide of human type I procollagen. Clin Chem 42:947-954.
- Chen P, Satterwhite JH, Licata AA, et al. 2005 Early changes in biochemical markers of bone formation predict BMD response to teriparatide in postmenopausal women with osteoporosis. J Bone Miner Res 20:962-970.
- Finkelstein JS, Leder BZ, Burnett SA, et al. 2006 Effects of teriparatide, alendronate, or both on bone turnover in osteoporotic men. J Clin Endocrinol Metab 91:2882-887.
- Nenonen A, Cheng S, Ivaska KK, et al. 2005 Serum TRACP 5b is a useful marker for monitoring alendronate treatment: comparison with other markers of bone turnover. J Bone Miner Res 20:1804-1812.
- Parikka V, Peng Z, Hentunen T, et al. 2005 Estrogen responsiveness of bone formation in vitro and altered bone phenotype in aged estrogen receptor deficient male and female mice. Eur J Endocrinol 152:301-314.
- Hale LV, Sells Galvin RJ, et al. 2007 PINP: A serum biomarker of bone formation in the rat. Bone.
- Product Code: AC-33F1
- Certification: Research Use Only
- RUO/IVD: RUO
- Number of Tests: 96 Wells
- Sample Type: Rat or mouse; serum and EDTA or heparin plasma
- Sample Volume: 5 µL
- Assay Range: 0.7 – 75 ng/mL
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