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Rat/Mouse PINP EIA

Product Description

For determination of N-terminal propeptide of type I procollagen (PINP) in rat or mouse serum or plasma samples.

  • Unique – the first commercially available EIA  to quantify type I collagen formation in rat or mouse specimens:
  • Ideal for rodents – only 5μL per well
  • Flexible – serum or plasma samples can be used
  • Complementary – use in conjunction with IDS RatTRAP™ (TRAcP 5b) ELISA or RatLaps® (CTX-I) EIA
  • Part of a complete assay panel supporting bone research
    1. Risteli J, Risteli L 2006 Products of bone collagen metabolism. In: Seibel MJ, Robins SP, BilezikianJP, editors. Dynamics of bone and cartilage metabolism. Principles and clinical applications, second edition. London: Academic Press. p. 391-405.
    2. Melkko J, Kauppila S, Niemi S, et al. 1996 Immunoassay for intact amino-terminal propeptide of human type I procollagen. Clin Chem 42:947-954.
    3. Chen P, Satterwhite JH, Licata AA, et al. 2005 Early changes in biochemical markers of bone formation predict BMD response to teriparatide in postmenopausal women with osteoporosis. J Bone Miner Res 20:962-970.
    4. Finkelstein JS, Leder BZ, Burnett SA, et al. 2006 Effects of teriparatide, alendronate, or both on bone turnover in osteoporotic men. J Clin Endocrinol Metab 91:2882-887.
    5. Nenonen A, Cheng S, Ivaska KK, et al. 2005 Serum TRACP 5b is a useful marker for monitoring alendronate treatment: comparison with other markers of bone turnover. J Bone Miner Res 20:1804-1812.
    6. Parikka V, Peng Z, Hentunen T, et al. 2005 Estrogen responsiveness of bone formation in vitro and altered bone phenotype in aged estrogen receptor deficient male and female mice. Eur J Endocrinol 152:301-314.
    7. Hale LV, Sells Galvin RJ, et al. 2007 PINP: A serum biomarker of bone formation in the rat. Bone.

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Rat/Mouse PINP EIA


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