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IDS Cortisol

Product Description

The IDS Cortisol assay is a fully automated CLIA assay for the quantitative determination of cortisol in human serum and plasma samples. Results are to be used in conjunction with other clinical and laboratory data to assist clinicians in the diagnosis and treatment of disorders of the adrenal gland.

  • Traceable to the Joint Committee for Traceability in Laboratory Medicine (JCTLM)-listed LC-MS/MS Candidate Reference Measurement Procedure (cRMP)for confidence in patient results
  • Utilises direct antibody coating immunoassay principle, removing the risk of inaccurate results due to biotin interference
  • Excellent functional sensitivity and precision over the clinically relevant range
  • Efficient laboratory workflow, consolidating the testing of ACTH, Aldosterone and Direct Renin on one fully automated platform from one plasma sample tube.
    1. Hawley JM et al. Candidate reference measurement procedure for the quantification of total serum cortisol with LC-MS/MS. Clin Chem 2016;62:262–9.
    2. Ramamoorthy, S. & Cidlowski, J. A. Corticosteroids: Mechanisms of Action in Health and Disease. Rheumatic diseases clinics of North America 42, 15-31, (2016).
    3. Wild, D. The immunoassay handbook. (Elsevier, 2005).
    4. Cain, D. W. & Cidlowski, J. A. Specificity and sensitivity of glucocorticoid signalling in health and disease. Best practice & research. Clinical endocrinology & metabolism 29, 545-556, (2015).
    5. Charmandari, E., Nicolaides, N. C. & Chrousos, G. P. Adrenal insufficiency. Lancet 383, 2152-2167, (2014).
    6. Findling, J. W. & Raff, H. Cushing’s Syndrome: important issues in diagnosis and management. The Journal of clinical endocrinology and metabolism 91, 3746-3753, (2006).
    7. Nieman, L. K. et al. The diagnosis of Cushing’s syndrome: an Endocrine Society Clinical Practice Guideline. The Journal of clinical endocrinology and metabolism 93, 1526-1540, (2008).

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IDS Cortisol

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