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IDS Urinary Cortisol

Product Description

The IDS Urinary Cortisol assay is a fully automated CLIA assay for the quantitative determination of cortisol in human urine samples. Results are to be used in conjunction with other clinical and laboratory data to assist clinicians in the diagnosis and monitoring of disorders of the adrenal gland.

  • Direct urine measurement, no extraction procedure required, for streamlined workflow
  • No risk of biotin interference by employing direct antibody-solid phase coating principle
  • Excellent functional sensitivity and precision over the clinically relevant range
  • Validated reference intervals in 24-hour urine collections from healthy subjects
  • Demonstrated clinical concordance in routine clinical samples
    1. Ramamoorthy, S. & Cidlowski, J. A. Corticosteroids: Mechanisms of Action in Health and Disease. Rheumatic diseases clinics of North America 42, 15-31, (2016).
    2. Wild, D. The immunoassay handbook. (Elsevier, 2005).
    3. Cain, D. W. & Cidlowski, J. A. Specificity and sensitivity of glucocorticoid signalling in health and disease. Best practice & research. Clinical endocrinology & metabolism 29, 545-556, (2015).
    4. Findling, J. W. & Raff, H. Cushing’s Syndrome: important issues in diagnosis and management. The Journal of clinical endocrinology and metabolism 91, 3746-3753, (2006).
    5. Raff, H. et al. Urine free cortisol in the diagnosis of Cushing’s syndrome: Is it worth doing and, if so, how? The Journal of clinical endocrinology and metabolism 100(2), 395-397, (2015).
    6. Nieman, L. K. et al. The diagnosis of Cushing’s syndrome: an Endocrine Society Clinical Practice Guideline. The Journal of clinical endocrinology and metabolism 93, 1526-1540, (2008).

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