IDS-iSYS Salivary Cortisol
Product Description
The IDS-iSYS Salivary Cortisol assay is intended for the quantitative determination of cortisol in human saliva on the IDS-iSYS Multi-Discipline Automated System family. Results are to be used as an aid in the assessment of Cushing’s and other disorders of the hypothalamic pituitary adrenal axis.
- The assay is fully automated, with less than 8 minutes time to first results, allowing you to efficiently provide accurate biologically active plasma free cortisol results
- The assay calibrators are traceable to an isotope dilution-mass spectrometry (ID-MS), from the Reference Institute for Bioanalytics (www.rfb.bio)
- The assay has excellent precision, functional sensitivity (0.02 µg/dL) and a wide assay measurable range (0.02-3.00µg/dL), giving you further confidence in the quality of assay results
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- John J. Bray et al. Lecture notes on human physiology. Third Edition Published by Blackwell Science 1994.
- David W., The Immunoassay Handbook. Third Edition. D.Wild (Ed.) Published by Elsevier Ltd. 2005.
- Yaneva M., Mosnier-Pudar H., Dugue M-A., Grabar S., Fulla Y. and Bertagna X., ‘Midnight salivary cortisol for the initial diagnosis of Cushing’s and various causes’. J Clin Endocrinol Metab, 89(7), 2004, pp 3345-3351.
- Aardal, E. and Holm, A-C., ‘Cortisol in saliva – reference ranges and relation to cortisol in serum’. Eur J Clin Chem Clin Biochem, 33, 1995, 927-932.
- Rossi GP., Seccia TM. and Pessina AC., ‘Clinical use of laboratory tests for the identification of secondary forms of arterial hypertension’. Crit Rev Clin Sci, 44(1), 2007, pp 1-85.
- Nieman LK., Biller BMK., Findling JW., Newell-Price J., Savage MO., Stewart PM., and Montori VM., ‘The diagnosis of Cushing’s: an endocrine society clinical practice guideline’. J Clin Endocrinol Metab, 93, 2008, pp 1526-1540.
- Raff, H., ‘Cushing’s: diagnosis and surveillance using salivary cortisol’. Pituitary, 15, 2012, pp 64-70.
- Raff, H., ‘Update on late-night salivary cortisol for the diagnosis of Cushing’s: methodological considerations’. Endocrine, 44, 2013, pp 346-349.
- Product Code: IS-4900
- Number of Tests: 100
- Sample Type: Saliva
- Sample Volume: 200 µL
- Assay Range: 0.02 – 3.00 µg/dL
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