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TRAcP 5b (BoneTRAP®)

Product Description

An automated assay for the quantitative determination of Tartrate Resistant Acid Phosphatase 5b (TRAcP 5b) in human serum and heparin plasma. The assay is intended for use as an aid in monitoring changes in bone metabolism in response to therapy.

  • Only automated solution for measurement of TRAcP 5b in patient sera
  • Only marker reflecting bone degradation suitable for use with renal patients
  • Only bone resorption marker unaffected by fasting status useful in samples taken at any time of day
  • Excellent sensitivity and reproducible results – providing a useful tool in therapy monitoring
  • Supported by a comprehensive portfolio of both bone formation and resorption markers
    1. Halleen JM. et al. Tartrate-resistant acid phosphatase 5b (TRACP 5b) as a marker of bone resorption. Clin Lab. 2006;52(9-10):499-509
    2. Halleen JM. et al. Serum Tartrate-resistant Acid Phosphatase 5b is a Specific and Sensitive Marker of Bone Resorption. Clin Chem. 2001;47(3):597-600
    3. Saunders PT. et al. The carbohydrate structure of porcine uteroferrin and the role of the high mannose chains in promoting uptake by the reticuloendothelial cells of the fetal liver. J Biol Chem. 1985;260:3658-3665.
    4. Hannon RA. et al. Clinical performance of immunoreactive tartrate resistant acid phosphatase isoform 5b as a marker of bone resorption. Bone. 2004; 34:187-194.

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TRAcP 5b (BoneTRAP®)

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