LISA-TRACKER Duo Trastuzumab
Product Description
LISA-TRACKER Duo Trastuzumab is an enzyme linked immunoassay (ELISA) for the quantitative determination of Trastuzumab (anti-HER2) and anti-Trastuzumab antibodies in human serum samples.
- Comprehensive menu in inflammatory diseases and oncology
- Validated on principle drug and biosimilars
- Ready to use reagents
- Standardised protocols from sample collection to result interpretation
- Automation ready – protocols available on several open platform ELISA systems
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- Boekhout A et al. Trastuzumab. Oncologist, 2011, 16, p.800-810.
- Damen C et al. Development and validation of an enzyme-linked immunosorbent assay for the quantification of Trastuzumab in human serum and plasma. Analytical Biochemistry, 2009, 391, p.114-120.
- Goldenberg MM et al. Trastuzumab, a recombinant DNA-derived humanized monoclonal antibody, a novel agent for the treatment of metastatic breast cancer. Clin. Ther., 1999, 21, p.309-318.
- Jamieson D et al. Development and validation of cell-based ELISA for the quantification of Trastuzumab in human plasma. Journal of immunological methods, 2009, 345, p. 106-111.
- Levêque D et al. Clinical Pharmacology of Trastuzumab. Current clinical Pharmacology, 2008, 3, 51-55.
- Molina MA et al. Trastuzumab (Herceptin), a humanized Anti-HER2 Receptor Monoclonal Antibody, Inhibits Basal and Activated HER2 Ectodomain Cleavage in Breast Cancer Cells. Cancer Research , 2001, 61, p. 4744-4749.
- Product Code: LTTR-005
- Number of Tests: 2 x 48
- Sample Type: Serum
- Sample Volume: 100 μL (following predilution)
- Assay Range: Trastuzumab: 10 – 200 μg/mL / Anti-Trastuzumab: 10 – 120 ng/mL
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