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LISA-TRACKER Duo Trastuzumab

Product Description

LISA-TRACKER Duo Trastuzumab is an enzyme linked immunoassay (ELISA) for the quantitative determination of Trastuzumab (anti-HER2) and anti-Trastuzumab antibodies in human serum samples.

  • Comprehensive menu in inflammatory diseases and oncology
  • Validated on principle drug and biosimilars
  • Ready to use reagents
  • Standardised protocols from sample collection to result interpretation
  • Automation ready – protocols available on several open platform ELISA systems
    1. Boekhout A et al.  Trastuzumab.  Oncologist, 2011, 16, p.800-810.
    2. Damen C et al.  Development and validation of an enzyme-linked immunosorbent assay for the quantification of Trastuzumab in human serum and plasma.  Analytical Biochemistry, 2009, 391, p.114-120.
    3. Goldenberg MM et al.  Trastuzumab, a recombinant DNA-derived humanized monoclonal antibody, a novel agent for the treatment of metastatic breast cancer.  Clin. Ther., 1999, 21, p.309-318.
    4. Jamieson D et al.  Development and validation of cell-based ELISA for the quantification of Trastuzumab in human plasma.  Journal of immunological methods, 2009, 345, p. 106-111.
    5. Levêque D et al.  Clinical Pharmacology of Trastuzumab.  Current clinical Pharmacology, 2008, 3, 51-55.
    6. Molina MA et al.  Trastuzumab (Herceptin), a humanized Anti-HER2 Receptor Monoclonal Antibody, Inhibits Basal and Activated HER2 Ectodomain Cleavage in Breast Cancer Cells.  Cancer Research , 2001, 61, p. 4744-4749.

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LISA-TRACKER Duo Trastuzumab

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