• Assure patient results – through standardisation to the ID-LCMS/MS Reference Method Procedure (RMP)
  • Actionable clinical assessment – of vitamin D status provided by measurement of total 25(OH) vitamin D with co-specificity of 25(OH) vitamin D3 and 25(OH) vitamin D2
  • Convenient reagent handling – with excellent stability combined with on-board storage and ready to use human serum calibrators and controls

An automated assay for the quantitative determination of total 25-hydroxyvitamin D [25(OH)D] in human serum and plasma on the IDS System. The results are used in conjunction with other clinical and laboratory data to assist the clinician in the assessment of vitamin D sufficiency.

Vitamin D is a fat-soluble vitamin naturally occurring, biologically inert hormone precursor that exists in two primary forms: vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol). Both forms are converted in the liver to the body’s main storage form of vitamin D, known as 25-hydroxyvitamin D [25(OH)D] and then in the kidneys to the physiologically active 1,25-dihydroxyvitamin D [1,25(OH)2D].

Total 25-hydroxyvitamin D [25(OH)D] concentration, the sum of 25(OH) D3 and 25(OH)D2, is considered as the best clinical indicator of vitamin D status. There are ongoing discussions over the 25(OH)D clinical cutpoints for vitamin D status. Many experts suggest that 25(OH)D level of > 30 ng/mL (75 nmol/L) gives optimal health benefits1,2.

  1. Holick MF, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an endocrine society clinical practice guideline, J Clin Endocrinol Metab 2011; 96 (7): 1911-1930.
  2. Rosen CJ, et al. IOM committee members respond to Endocrine Society vitamin D guideline. J Clin Endocrinol Metab. 2012 Apr;97(4):1146-52.

IDS-iSYS 1,25-Dihydroxy Vitamin D

IDS-iSYS 1,25 VitDXp*


IDS-iSYS Ostase® BAP*


IDS-iSYS TRAcP 5b (BoneTRAP®)*

IDS-iSYS InaKtif MGP (dp-ucMGP)*


* Available in selected markets, product availability subject to required regulatory approval.

NB: Ostase® is a registered trademark of Hybritech Incorporated, a subsidiary of Beckman Coulter, Inc.