- Unique and proprietary immunocapsules – simplifies the sample purification procedure and eliminates the need for organic solvents
- Reliable and consistent automated acridinium ester magnetic particles chemiluminescence immunoassay – delivers consistent results and improves laboratory workflow
- Automated immunoassay – replaces extensive lab bench time radioactive immunoassay
- Seamless transition to automated test
- Improves technologist productivity
- Cost-effective, eliminates the need for organic solvents
The IDS-iSYS 1,25-Dihydroxy Vitamin D assayis a complete assay system intended for the purification of 1,25-dihydroxyvitamin D [1,25D] in human serum or plasma by immunopurification followed by quantitative determination on the IDS-iSYS Multi-Discipline Automated System to assess 1,25-dihydroxyvitamin D deficiency associated with renal disease.
1,25-dihydroxyvitamin D (1,25(OH)2D) is the biologically active metabolite of vitamin D that plays a key role in the regulation of calcium and phosphate homeostasis. Measurement of 1,25(OH)2D is important in managing patients with renal failure, hyperphosphataemia, hypomagnesaemia, hypoparathyroidism, pseudohyperparathyroidism, vitamin D dependent rickets, granulomatous disease, lymphoma, primary hyperparathyroidism and hypercalcaemia.
Endres DB, Rude RK. Mineral and bone metabolism. In: Burtis CA, Ashwood ER, Bruns DE, editors. Tietz textbook of clinical chemistry and molecular diagnostics. St. Louis: Elsevier Saunders; 2006. p. 1891–965.
Holick, MF., et al. “Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline.” The Journal of Clinical Endocrinology & Metabolism 96.7 (2011): 1911-1930.
Gadisseur R., et al. Performance of the IDS-iSYS 1, 25-dihydroxy vitamin D assay. Poster. AACC 2013.