i-Tracker anti-Certolizumab
Product Description
i-Tracker anti-Certolizumab is an automated assay intended for the quantitative measurement of anti Certolizumab antibodies (anti-drug antibodies: ADAb) in human serum or plasma samples.
- Innovative CLIA technology
- Quantitative measurement of drug and anti-drug antibodies
- First results in less than 35 minutes; 60 results/hour
- Validated on princeps and biosimilars
- Controls and calibrators included
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- Vande Casteele N, Feagan B, Vermeire S, et al. Covariates influencing the exposure-response relationship for certolizumab pegol during the induction and maintenances phases in patients with Crohn’s disease. Am J Gastroenterol 2016;111:S262–S263.
- Vande Casteele, N., Feagan, B.G., Vermeire, S. et al. Exposure–response relationship of certolizumab pegol induction and maintenance therapy in patients with Crohn’s disease. Aliment Pharmacol Ther. 2018; 47: 229–237
- Colombel JF, Sandborn WJ, Allez M, et al. Association Between Plasma Concentrations of Certolizumab Pegol and Endoscopic Outcomes of Patients With Crohn’s Disease. Clinical Gastroenterology and Hepatology 2014;12:423–431
- Paul S, et al.. Exposure-Response Relationship of Certolizumab Pegol and Achievement of Low Disease Activity and Remission in Patients With Rheumatoid Arthritis. Clin Transl Sci. 2020 Jul;13(4):743-751.
- S. Paul, et al. Exposure-Response Relationship Of Certolizumab Pegol And Achievement of Low Disease Activity and Remission In Patients with rheumatoid arthritis. Clin Transl Sci 2020 Feb 26
- Gehin JE, Goll GL, Warren DJ, et al. Anti-drug antibodies to certolizumab pegol are associated with low drug levels and reduced clinical response at 3 months in patients with inflammatory joint diseases. data from the nor-dmard study. Annals of the Rheumatic Diseases 2018;77:844
- Product Code: CTC 003-50
- Number of Tests: 50
- Sample Type: Serum or plasma
- Sample Volume: 100 µL
- Assay Range: 10 - 1500 AU/mL
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