- Most important serological markers: automated quantitative Total and Specific IgE
- Traceable against the WHO 2nd International Standard for Human IgE 75/502
- Clinically relevant and most prominent allergens
- Components and extracts for specific and sensitive results
- Aligned closely with recognised test guidelines (2)
- Well correlated to another supplier
- Rapidly increasing panel
An automated assay for the quantitative determination of Specific IgE in human serum on the IDS System. The results are to be used as an aid in the diagnosis and management of allergic disorders in conjunction with other clinical findings. The presence of allergen-specific IgE antibodies in serum is referred to as sensitisation and is an important risk factor for allergic reactions upon re-exposure to the allergen (1).
House dust mites are important risk factors for allergic rhinitis, asthma and atopic dermatitis. Dermatophagoides pteronyssinus belong to the most recognized house dust mites. The dust mite components Der p 1 and Der p 2 are major allergens of D. pteronyssinus and specific markers for primary sensitisation. Der p 10 is considered a minor allergen and marker of cross-reactivity between mites, crustaceae, insects and molluscs. Components can be useful in identifying patients that will respond to Immunotherapy (2).
- Hamilton RG. Allergic sensitization is a key risk factor for but not synonymous with allergic disease. J Allergy Clin Immunol. 2014 Aug;134(2):360-1
- Matricardi PM, Kleine-Tebbe J, Hoffmann HJ, Valenta R, Hilger C, et al. EAACI Molecular Allergology User’s Guide. Pediatr Allergy Immunol. 2016 May;27 Suppl 23:1-250