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Product Description

The EBV VCA IgM test is a chemiluminescent immunoassay (CLIA), for use on IDS automated analyzers, for quantitative determination of specific IgM class antibodies directed against the Epstein-Barr viral capsid antigen (VCA) in samples of human serum or plasma (K3-EDTA, Sodium Citrate).

The assay is used as a diagnostic aid when assessing infective mononucleosis (IM).

  • Complete panel available for the detection of the EBV infection
  • Early detection of EBV VCA IgM in the sera of infected people
  • High sensitivity and specificity of the VCA IgM test in the acute infection
  • High specificity and sensitivity of the 3 tests VCA IgG , VCA IgM and EBNA-1 IgG when used together to evaluate the stage of the infection
    1. Rickinson AB, Kieff E. Epstein-Barr virus. In: Knipe DM, Howley PM, Griffin DE, Martin MA, Lamb RA, editors. Fields virology. Philadelphia: Lippincott Williams and Wilkins;2001, pp 2575-2627
    2. Steven NM. Infectious mononucleosis. EBV Reports. 1996; 3: 91-95
    3. Tatsumi E, Purtilo DT. Epstein-Barr virus ( EBV ) and X-linked lymphoproliferative syndrome ( XLP ). AIDS Res. 1986 Dec; 2 Suppl 1 : S109-13
    4. Maeda E, Akahane M, Kiryu S, et al ( January 2009 ). “ Spectrum opf Epstein-Barr virus related diseases : a pictorial review “. Jpn J Radiol 27 ( 1 ) : 4-19
    5. Toussirot E, Roudier J ( October 2008 ). “ Epstein-Barr virus in autoimmune diseases “.  Best Practice & Research. Clinical Rheumatology 22 (5) : 883-96
    6. Godshall S.E. and J. T. Kirchner. 2000. Infectious mononucleosis. Complexities of a common syndrome. Postgrad. Med.107 :175-179, 183-184,186.
    7. Lennette E.T. 1995. Epstein-Barr virus (EBV), p. 299-312. In E.H. Lennette , D.A. Lennette, and E.T. Lennette (ed), Diagnostic procedures for viral,rickettsial, and chlamydial infections,7th American Public Health Association,Washington,D.C.
    8. Hess RD. Routine Epstein-Barr virus diagnostics from the laboratory perspective : still challenging after 35 years. J. Clin Microbiol. 2004; 42:3381-3387

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