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CCP

Product Description

The CCP test is a chemiluminescent immunoassay (CLIA), for use on IDS automated analyzers. It is used for the quantitative determination of the specific IgG antibodies directed against cyclic citrullinated peptide (CCP), in human samples of serum or plasma (EDTA and Heparin).

    1. Wener MH. Rheumatoid Factors. Manual of Clinical Laboratory Immunology, NR Rose et al. American Society of Microbiology Press, 961-972 ( 2002 ).
    2. Schellekens GA, Visser H, De Jong BA, Van de Hoogen FH, Hazens JM, Breedveld FC, et al. The diagnostic properties of rheumatoid arthritis recognizing a cyclic citrullinated peptide. Arthritis Rheum 2000; 43: 155-63.
    3. Baeten D, Peene I, Union A, Sebbag M, Serre G, Veys EM, et al. Specific presence of intracellular citrullinate proteins in rheumatoid arthritis synovium: relevance to antifilaggrin antibodies. Arthritis Rheum 2001; 44: 2218-62.
    4. Asaga H, Yamada M, Senshu T. Selective determination of vimentin in calcium ionophore-induced apoptosis of mouse peritoneal macrophages. Biochem Biophys Res Commun 1998; 243: 641-6.
    5. Verpoort KN, van Gaalen FA, van der Helm-van et al. Association of HLA-DR3 with anti-cyclic citrullinated peptide antibody-negative rheumatoid arthritis. Arthritis Rheum 2005; 52:3058-62.
    6. Bizzaro N, Mazzanti G, Tonutti E et al. Diagnostic accuracy of the anti-citrulline antibody assay for rheumatoid arthritis. Clin Chem 2001; 47: 1089-93.
    7. Van Gaalen FA, Visser H, Huizinga TW. A comparison of the diagnostic accuracy and prognostic value of the first and second anti-cyclic citrullinated peptides autoantibody tests for rheumatoid arthritis. Ann Rheum Dis 2005; 64: 1510-2.
    8. Rantapaa-Dahlqvist S, de Jong BAW, Berglin E et al. Antibodies against cyclic citrullinated peptide and IgA rheumatoid factor predict the development of rheumatoid arthritis. Arthritis Rheum 2003; 48: 2741-9.
    9. Visser H, le Cessie S, Vos K et al. How to diagnose rheumatoid arthritis early. A prediction model for persistent (erosive) arthritis. Arthritis Rheum 2002; 46: 357-65.
    10. Jansen LMA, van der Horst-Bruinsma IE, van Shaardenburg D, van de Stadt RJ, de Koning MHMT, Dukmans BAC. Rheumatoid factor and antibodies to cyclic citrullinated peptide differentiate rheumatoid arthritis from undifferentiated polyarthritis in patients with early arthritis. J Rheumatol 2002; 29( 10 ): 2074-2076.
  • Product Code: IS-AI1201
  • Number of Tests: 100
  • Sample Type: Human Serum or Plasma (EDTA and Heparin)
  • Sample Volume: 4 µL
  • Assay Range: 0-320 AU/mL
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