- Exceptional sensitivity and highly reproducible results
- Suitable for measurement of a variety of sample types
- Excellent correlation with existing 17-OH Progesterone ELISA assays
- Fully automated assay
- All reagents are ready to use
The IDS-iSYS 17-OH Progesterone assay is an in vitro diagnostic device intended for the quantitative determination of 17-OH Progesterone in human serum or plasma on the IDS-iSYS Multi-Discipline Automated System.
Results are to be used as an aid in the diagnosis and treatment of various disorders of the adrenal glands or the ovaries.
17-Hydroxyprogesterone (17-OH P) is a steroid hormone produced in both the adrenal gland and gonads which is synthesised from either progesterone or 17-hydroxypregnenolone. It functions as a precursor of cortisol in the adrenal glands or is converted into androgenic and estrogenic hormones.
Measurement of 17-OH P is used in the assessment of 21-hydroxylase deficiency which is linked to congenital adrenal hyperplasia (CAH).
Dunn, J.F., Nisula, B.C., Rodbart, D: Transport of steroid hormones: Binding of 21 endogenous steroids to both testosterone-binding globuline and corticosteroid-binding globulin in human plasma. J.Clin.Endocrin.Metabol 53(1), 58-68, 1981