U1-snRNP
Product Description
The U1-snRNP test is a chemiluminescent immunoassay (CLIA), for use on IDS automated analyzers. It is used for the quantitative determination of the specific IgG antibodies directed against the U1-snRNP antigens in human samples of serum or plasma (EDTA).
-
- CA von Mühlen, EM Tan. Autoantibodies in the diagnosis of systemic rheumatic diseases. Sem Arthr Rheum 1995; 24: 323-58.
- RL Humbel. Auto-immunité, auto-anticorps et maladie. In : Humbel RL, ed. Autoanticorps et maladies autoimmunes, Paris, France : Edition Scientifiques Elsevier; 1997: 17-20.
- PN Hollingsworth, SC Pummer, RL Dawkins. Antinuclear antibodies. In : Peter JB, Shoenfeld Y, eds. Autoantibodies. Amsterdam, The Netherlands : Elsevier Science BV; 1996: 74-90.
- CA Slater, RB Davis, RH Shmerling. Antinuclear antibodies testing. A study of clinical utility. Arch Int Med 1996; 156: 1421-5.
- RL Humbel. Detection of antinuclear antibodies by immunofluorescence. In : van Venrooij, Maini RN eds. Manual of Biological Markers of Disease. Dordrecht, The Netherlands : Kluwer; 1993: A2:1-16.
- National Committee for Clinical Laboratory Standardization. Quality assurance for the indirect immunofluorescence test for autoantibodies to nuclear antigen ( IF-ANA ). Approved Guideline. Wayne, PA: NCCLS I/LA2-A, vol. 16 ( 11 ); 1996.
- CL Will, R Luhrmann. Spliceosomal UsnRNP biogenesis, structure and function. Curr Opin Cell Biol 2001; 13:290-301.
- GW Zieve, PR Khusial. The anti-Sm immune response in autoimmunity and cell biology. Autoimmun Rev 2003; 2: 235-40.
- MT McClain, PA Ramsland, KM Kaufman, JA James. Anti-Sm autoantibodies in systemic lupus erythematosus target highly basic surface structures of complexed spliceosomal autoantigens. J Immunol 2002; 168: 2054-62.
- SL Peng, JE Craft. Spliceosomal snRNPs autoantibodies. In : Peter JB, Shoenfeld Y, eds. Autoantibodies. Amsterdam : Elsevier Science BV, 1996, pages 774-82.
- Y Sherer, A Gorstein, MJ Fritzler, Y Shoenfeld. Autoantibody explosion in systemic lupus erythematosus. Semin Arthritis Rheum 2004; 34: 501-37.
- Product Code: IS-AI1107
- Number of Tests: 50
- Sample Type: Human Serum or Plasma (EDTA)
- Sample Volume: 4 µL
- Assay Range: 0-240 AU/mL
- Add to Enquiry Basket
Interested? Enquire now.
Add to Enquiry Basket
Related Products
Assays | Certification | Platform | Clinical Area | Portfolio | RUO/IVD |
---|---|---|---|---|---|
SS-B/La | CE Marked | i10iSYS | Connective Tissue Disease | Autoimmunity | IVD |
ANA Screen | CE Marked | i10iSYS | Connective Tissue Disease | Autoimmunity | IVD |
ENA Screen | CE Marked | i10iSYS | Connective Tissue Disease | Autoimmunity | IVD |
Centromere B | CE Marked | i10iSYS | Connective Tissue Disease | Autoimmunity | IVD |