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LISA-TRACKER Rituximab

Product Description

LISA-TRACKER Rituximab is an enzyme linked immunoassay (ELISA) for the quantitative determination of Rituximab (anti-CD20) in human serum samples.

  • Comprehensive menu in inflammatory diseases and oncology
  • Validated on principle drug and biosimilars
  • Ready to use reagents
  • Standardised protocols from sample collection to result interpretation
  • Automation ready – protocols available on several open platform ELISA systems
    1. Cartron G et al. Pharmacokinetics of rituximab and its clinical use: Thought for the best use? Critical Reviews in Oncology/Hematology 62 (2007) 43-52.
    2. Huhn D et al. Rituximab therapy of patients with B-cell chronic lymphocytic leukemia. Blood, 2001; 98: 1326-1331.
    3. Breedveld F et al. Rituximab pharmacokinetics in patients with Rheumatoid Arthritis: B-Cell levels do not correlate with clinical response. Journal of Clinical Pharmacology, 2007; 47:1119-1128.
    4. Nakou M et al. Rituximab therapy reduces activated B cells in both the peripheral blood and bone marrow of patients with rheumatoid arthritis: depletion of memory B cells correlates with clinical response. Arthritis Research & Therapy 2009, 11:R131.
    5. Cragg MS et al. A new anti-idiotype antibody capable of binding rituximab on the surface of lymphoma cells. Blood. 2004;104:2540-2542.
    6. Thurlings RM et al. Clinical response, pharmacokinetics, development of human anti-chimaeric antibodies, and synovial tissue response to rituximab treatment in patients with rheumatoid arthritis. Ann Rheum Dis 2010; 69: 409–412.

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LISA-TRACKER Rituximab

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