• Comprehensive menu in inflammatory diseases and oncology
  • Validated on principle drug and biosimilars
  • Ready to use reagents
  • Standardised protocols from sample collection to result interpretation
  • Automation ready – validated on several open platform ELISA systems

LISA-TRACKER anti-Bevacizumab is an enzyme linked immunoassay (ELISA) for the quantitative determination of anti-Bevacizumab antibodies in human serum samples.

Bevacizumab is a humanised monoclonal antibody that produces angiogenesis inhibition by inhibiting the Vascular Endothelial Growth Factor (VEGF). It is indicated for the treatment of many cancers (colorectal, lung, breast, renal, ovarian, brain etc.) as it suppresses the action of the VEGF responsible for the growth of tumours.  However, during the treatment, some patients can develop antibodies against Bevacizumab.

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  • Gilbert R et al. A randomized trial of bevacizumab for newly diagnosed glioblastoma, N Engl J Med, 2014; 370:699-708.
  • Huang H.  An updated meta-analysis of fatal adverse events caused by Bevacizumab therapy in cancer patients. PLoS One, 2014, 9(3): e89960.
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  • Nugue G. Monitoring Monoclonal antibody delivery in oncology: the example of Bevacizumab. PLoS One. 2013, 8(8): e72021.
  • Parikh S.S. Advances in development of Bevacizumab, a humanized anti-angiogenic therapeutic monoclonal antibody targeting VEGF in cancer cells. Int. J. Pharm. Biomed. Sci 2012, 3(4), 155-163.
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LISA-TRACKER Duo Bevacizumab

LISA-TRACKER Bevacizumab

ImmunoTROL LISA-TRACKER Bevacizumab

ImmunoTROL LISA-TRACKER anti-Bevacizumab