- Comprehensive menu in inflammatory diseases and oncology
- Validated on principle drug and biosimilars
- Ready to use reagents
- Standardised protocols from sample collection to result interpretation
- Automation ready – validated on several open platform ELISA systems
LISA-TRACKER anti-Bevacizumab is an enzyme linked immunoassay (ELISA) for the quantitative determination of anti-Bevacizumab antibodies in human serum samples.
Bevacizumab is a humanised monoclonal antibody that produces angiogenesis inhibition by inhibiting the Vascular Endothelial Growth Factor (VEGF). It is indicated for the treatment of many cancers (colorectal, lung, breast, renal, ovarian, brain etc.) as it suppresses the action of the VEGF responsible for the growth of tumours. However, during the treatment, some patients can develop antibodies against Bevacizumab.
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- Parikh S.S. Advances in development of Bevacizumab, a humanized anti-angiogenic therapeutic monoclonal antibody targeting VEGF in cancer cells. Int. J. Pharm. Biomed. Sci 2012, 3(4), 155-163.
- Perren T.J. A phase 3 trial of bevacizumab in ovarian cancer. The New England journal of medicine, vol. 365, no 26, 2011, p. 2484-2496.
- Sinapis C. Pharmacokinetics of intravitreal Bevacizumab (Avastin) in rabbits. Clinical Ophtalmology, 2011:5, 698-704.
- Ternant D. An enzyme-Linked Immunosorbent Assay to study Bevacizumab Pharmacokinetics. The Drug Monit 2010; 32:647-652.
LISA-TRACKER Duo Bevacizumab
ImmunoTROL LISA-TRACKER Bevacizumab
ImmunoTROL LISA-TRACKER anti-Bevacizumab