- Most important serological markers: automated quantitative Total and Specific IgE
- Traceable against the WHO 2nd International Standard for Human IgE 75/502
- Clinically relevant and most prominent allergens
- Components and extracts for specific and sensitive results
- Aligned closely with recognised test guidelines (2)
- Well correlated to another supplier
- Rapidly increasing panel
An automated assay for the quantitative determination of Specific IgE in human serum on the IDS System. The results are to be used as an aid in the diagnosis and management of allergic disorders in conjunction with other clinical findings. The presence of allergen-specific IgE antibodies in serum is referred to as sensitisation and is an important risk factor for allergic reactions upon re-exposure to the allergen (1).
Grass pollen allergy is a global problem and sensitised subjects suffer from symptoms of allergic rhinoconjunctivitis and/or bronchial asthma, particularly during the warm seasons(2). The Grass mix 3 contains grass extracts from the Pooideae subfamily, i.e. Sweet vernal grass (Anthoxanthum odoratum), Rye-grass (Lolium perenne), Timothy grass (Phleum pratense), Cultivated rye (Secale cereale) and Velvet grass (Holcus lanatus). The grasses are found in regions with temperate climate. Phl p 1 and Phl p 5b are major allergens and specific marker for grass pollens of the Pooideae subfamily. The components can be useful in identifying patients that will respond to Immunotherapy (3).
- Hamilton RG. Allergic sensitization is a key risk factor for but not synonymous with allergic disease. J Allergy Clin Immunol. 2014 Aug;134(2):360-1
- Global Atlas of Allergy. Published by the European Academy of Allergy and Clinical Immunology.2014
- Matricardi PM, Kleine-Tebbe J, Hoffmann HJ, Valenta R, Hilger C, et al. EAACI Molecular Allergology User’s Guide. Pediatr Allergy Immunol. 2016 May;27 Suppl 23:1-250
- IDS Total IgE / Specific IgE Reagent Kit
- IDS Total IgE Control Set
- IDS Positive and Negative Specific IgE Controls