- Fully on-board samples purification with proven and trusted antibody specificity
- Confidence in patients results though the established automated immunoassay
- Excellent stability combined with on-board storage convenience and reagent handling
Fully automated assay for the quantitative determination of 1,25-dihydroxyvitamin D [1,25(OH)2D] in human serum to assess 1,25-dihydroxyvitamin D deficiency associated with renal disease.
1,25-dihydroxyvitamin D (1,25(OH)2D) is the biologically active metabolite of vitamin D that plays a key role in the regulation of calcium and phosphate homeostasis. Measurement of 1,25(OH)2D is important in managing patients with renal failure, hyperphosphatemia, hypomagnesemia, hypoparathyroidism, pseudohyperparathyroidism, vitamin Ddependent rickets, granulomatous disease, lymphoma, primary hyperparathyroidism, and hypercalcemia.
Kidney Disease: Improving Global Outcomes (KDIGO) CKD-MBD Work Group. KDIGO clinical practice guideline for the diagnosis, evaluation, prevention, and treatment of chronic kidney disease-mineral and bone disorder (CKD-MBD).
Holick, MF., et al. “Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline.” The Journal of Clinical Endocrinology & Metabolism 96.7 (2011): 1911-1930.
Tran J., et al. A fully Automated 1,25-Dihydroxy Vitamin D Assay on the IDS-iSYS Automated System. Poster. AACC 2014.